David M Lee Selected Research

osteoblast cadherin

5/2015	Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism.
5/2011	Cadherin-11 regulates fibroblast inflammation.
5/2009	Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes.
4/2008	Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.
2/2007	Cadherin-11 in synovial lining formation and pathology in arthritis.
5/2006	Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro.
12/2004	Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes.

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David M Lee Research Topics

Disease

29	Arthritis (Polyarthritis) 11/2011 - 02/2002
25	Rheumatoid Arthritis 01/2020 - 02/2002
18	Inflammation (Inflammations) 12/2013 - 01/2005
6	Synovitis 04/2011 - 05/2005
5	Osteoarthritis 05/2015 - 01/2007
4	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 04/2002
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2014 - 12/2009
4	Psoriatic Arthritis 04/2013 - 04/2003
4	Hypogonadism (Hypergonadotropic Hypogonadism) 06/2012 - 04/2010
4	Experimental Arthritis 07/2010 - 10/2006
3	Cognitive Dysfunction 01/2022 - 06/2017
3	Psoriasis (Pustulosis Palmaris et Plantaris) 03/2017 - 04/2013
3	Pain (Aches) 01/2016 - 02/2011
2	Infertility (Sterility) 01/2017 - 04/2005
2	Joint Diseases (Joint Disease) 01/2015 - 01/2007
2	Neoplasms (Cancer) 07/2014 - 12/2007
2	Prostatic Neoplasms (Prostate Cancer) 08/2013 - 02/2011
2	Carcinoma (Carcinomatosis) 08/2013 - 02/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 04/2013 - 05/2012
2	Spondylarthropathies 04/2013 - 04/2003
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2013 - 01/2011
2	Insulin Resistance 05/2012 - 12/2009
2	Weight Loss (Weight Reduction) 01/2011 - 10/2008
2	Necrosis 08/2009 - 11/2008
2	Infections 11/2008 - 04/2008
1	Heart Arrest (Cardiac Arrest) 01/2021
1	Small Cell Carcinoma 05/2019
1	Dementia (Dementias) 09/2017
1	Obesity 01/2016
1	Soft Tissue Infections 09/2015
1	Hematoma 09/2015

Drug/Important Bio-Agent (IBA)

10	AutoantibodiesIBA 10/2013 - 09/2002
9	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2007
8	CytokinesIBA 01/2020 - 01/2005
7	osteoblast cadherinIBA 05/2015 - 12/2004
6	Leukotriene B4IBA 10/2012 - 04/2006
6	LipidsIBA 04/2011 - 05/2008
5	Vitamin D FDA LinkGeneric 09/2017 - 12/2009
5	25-hydroxyvitamin DIBA 09/2017 - 12/2009
5	hydroxide ionIBA 09/2017 - 12/2009
5	Complement System Proteins (Complement)IBA 04/2013 - 09/2002
5	EnzymesIBA 10/2012 - 04/2002
5	Tryptases (Tryptase)IBA 01/2011 - 04/2008
4	Hormones (Hormone)IBA 01/2022 - 07/2011
4	secukinumabIBA 03/2017 - 04/2013
4	AntibodiesIBA 07/2015 - 04/2002
4	ChemokinesIBA 05/2015 - 05/2005
4	AntigensIBA 10/2013 - 03/2006
4	Immunoglobulin G (IgG)IBA 04/2013 - 08/2010
4	Fc Receptors (Fc Receptor)IBA 10/2010 - 09/2002
3	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2022 - 07/2011
3	Interleukin-17 (Interleukin 17)IBA 03/2017 - 04/2013
3	Monoclonal AntibodiesIBA 01/2016 - 05/2005
3	Parathyroid Hormone (Parathormone)IBA 07/2014 - 12/2009
3	LeukotrienesIBA 10/2012 - 04/2006
3	Testosterone (Sustanon)FDA Link 06/2012 - 04/2010
3	Peptide Hydrolases (Proteases)FDA Link 11/2011 - 08/2008
3	Anaphylatoxin C5a ReceptorIBA 02/2011 - 03/2010
3	CollagenIBA 01/2010 - 06/2007
3	Tyrosine (L-Tyrosine)FDA Link 01/2010 - 05/2005
3	Immunoglobulins (Immunoglobulin)IBA 04/2003 - 02/2002
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 03/2010
2	1,25-dihydroxyvitamin DIBA 09/2017 - 07/2014
2	C-Reactive ProteinIBA 06/2017 - 11/2010
2	Biomarkers (Surrogate Marker)IBA 03/2017 - 04/2013
2	HLA-DRB1 Chains (HLA DRB1)IBA 01/2016 - 10/2010
2	InterleukinsIBA 07/2015 - 04/2013
2	EpitopesIBA 01/2015 - 10/2010
2	Chemokine ReceptorsIBA 12/2013 - 01/2009
2	AndrogensIBA 05/2012 - 02/2011
2	Peptides (Polypeptides)IBA 03/2012 - 12/2010
2	Carboxypeptidase BIBA 09/2011 - 10/2009
2	Interleukin-6 (Interleukin 6)IBA 05/2011 - 10/2008
2	Rheumatoid FactorIBA 04/2011 - 10/2010
2	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 11/2010 - 03/2010
2	Antigen-Antibody Complex (Immune Complex)IBA 11/2010 - 05/2010
2	Protein Isoforms (Isoforms)IBA 10/2010 - 05/2008
2	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 03/2010 - 03/2005
2	Interleukin-1 (Interleukin 1)IBA 03/2010 - 02/2007
2	Imatinib Mesylate (Gleevec)FDA Link 01/2010 - 10/2006
2	Phosphotransferases (Kinase)IBA 01/2010 - 10/2006
2	Prostaglandins EIBA 08/2009 - 11/2008
2	Heparin (Liquaemin)FDA LinkGeneric 01/2009 - 08/2008
2	Dinoprostone (PGE2)FDA Link 11/2008 - 05/2008
2	ProstaglandinsIBA 11/2008 - 05/2008
2	Glucose-6-Phosphate Isomerase (Phosphoglucose Isomerase)IBA 04/2003 - 04/2002
1	Androgen Receptors (Androgen Receptor)IBA 01/2022
1	Member 25 Tumor Necrosis Factor ReceptorsIBA 01/2020
1	DefensinsIBA 03/2017
1	Mitochondrial DNA (mtDNA)IBA 01/2017
1	VitaminsIBA 01/2016
1	TitaniumIBA 09/2015
1	Cell Adhesion MoleculesIBA 05/2015
1	Matrix Metalloproteinases (MMPs)IBA 05/2015

Therapy/Procedure

5	Therapeutics 03/2017 - 02/2007
1	Resuscitation 01/2021
1	Cardiopulmonary Resuscitation (CPR) 01/2021
1	Ovariectomy (Oophorectomy) 05/2019
1	Replantation 09/2015
1	Reoperation 09/2015